{"id":3695,"date":"2025-03-27T07:54:14","date_gmt":"2025-03-27T06:54:14","guid":{"rendered":"https:\/\/health.mymagnolia.nl\/?page_id=3695"},"modified":"2025-04-03T09:08:33","modified_gmt":"2025-04-03T07:08:33","slug":"research","status":"publish","type":"page","link":"https:\/\/health.mymagnolia.nl\/en\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3695\" class=\"elementor elementor-3695 elementor-3694\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-35548b8 e-flex e-con-boxed e-con e-parent\" data-id=\"35548b8\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2b621bfa e-con-full e-flex e-con e-child\" data-id=\"2b621bfa\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-bd732b9 e-con-full e-flex e-con e-child\" data-id=\"bd732b9\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3b8638d6 elementor-widget elementor-widget-heading\" data-id=\"3b8638d6\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Research on Psilocybin<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-489ad elementor-widget elementor-widget-text-editor\" data-id=\"489ad\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><strong>An Overview of Completed Studies<\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a6ebe4b elementor-widget elementor-widget-text-editor\" data-id=\"4a6ebe4b\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p class=\"\" data-start=\"118\" data-end=\"565\">In recent years, research into psilocybin has yielded promising insights into its potential therapeutic applications. In controlled settings, psilocybin has shown positive effects on a range of mental health conditions. While the results are encouraging, experts caution against the use of psilocybin outside of professional and controlled environments. The substance has a powerful effect on the psyche and can pose risks without proper guidance.<\/p>\n<p data-start=\"118\" data-end=\"565\">\u00a0<\/p>\n<p class=\"\" data-start=\"567\" data-end=\"653\">Below is an overview of completed studies, including their goals, setup, and findings.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-226b25b5 e-flex e-con-boxed e-con e-parent\" data-id=\"226b25b5\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-5a36f790 e-con-full e-flex e-con e-child\" data-id=\"5a36f790\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4c6ecff e-con-full pf-filter e-flex e-con e-child\" data-id=\"4c6ecff\" data-element_type=\"container\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;],&quot;sticky_offset&quot;:150,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;sticky_effects_offset&quot;:0,&quot;sticky_anchor_link_offset&quot;:0}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-29b0b324 elementor-widget elementor-widget-heading\" data-id=\"29b0b324\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">An Overview of Completed Studies<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-10405111 elementor-widget elementor-widget-shortcode\" data-id=\"10405111\" data-element_type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><div class=\"facetwp-facet facetwp-facet-categories facetwp-type-checkboxes\" data-name=\"categories\" data-type=\"checkboxes\"><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-6716a3d0 e-con-full pf-posts e-flex e-con e-child\" data-id=\"6716a3d0\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-527adb02 elementor-widget elementor-widget-shortcode\" data-id=\"527adb02\" data-element_type=\"widget\" data-widget_type=\"shortcode.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-shortcode\"><div class=\"facetwp-facet facetwp-facet-inzichten_pager facetwp-type-pager\" data-name=\"inzichten_pager\" data-type=\"pager\"><\/div><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76bf1f2a elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"76bf1f2a\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Psilocybin for Depression (MDD \u2013 Major Depressive Disorder)<\/h3><p class=\"elementor-image-box-description\"><ul>\n  <li><strong>Study:<\/strong> Randomized clinical trial (JAMA Network)<\/li>\n  <li><strong>Design:<\/strong> Participants received a single dose of psilocybin or a placebo.<\/li>\n  <li><strong>Results:<\/strong> The psilocybin group showed a significant reduction in depressive symptoms. These effects lasted up to 43 days.<\/li>\n\n  <br>\n  <a href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2772630\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-444c761e elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"444c761e\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Behandeling van Therapieresistente Depressie (TRD)<\/h3><p class=\"elementor-image-box-description\"><li><strong>Study:<\/strong> Phase 2b study by COMPASS Pathways (New England Journal of Medicine, 2022)<\/li>\n  <li><strong>Design:<\/strong> 233 patients from 10 countries received a single dose of psilocybin (1 mg, 10 mg, or 25 mg), with psychological support.<\/li>\n  <li><strong>Results:<\/strong> After 3 weeks, 29% of the 25 mg group were in remission, compared to 8% in the 1 mg group. Some effects lasted up to 12 weeks. Side effects were mild (e.g., headache). This was the largest psilocybin study to date.<\/li>\n\n  <br>\n  <a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa2206443\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7e28a22 elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"7e28a22\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Langetermijneffecten op Depressie<\/h3><p class=\"elementor-image-box-description\"><li><strong>Study:<\/strong> Johns Hopkins University (Johns Hopkins Medicine)<\/li>\n  <li><strong>Design:<\/strong> Follow-up after two psilocybin sessions.<\/li>\n  <li><strong>Results:<\/strong> The majority of participants maintained reduced depressive symptoms up to one year after treatment.<\/li>\n\n  <br>\n  <a href=\"https:\/\/www.hopkinsmedicine.org\/news\/newsroom\/news-releases\/2022\/02\/psilocybin-treatment-for-major-depression-effective-for-up-to-a-year-for-most-patients-study-shows\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ee68f9e elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"4ee68f9e\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Angst en Depressie bij Kankerpati\u00ebnten<\/h3><p class=\"elementor-image-box-description\"><li><strong>Study:<\/strong> Johns Hopkins (2016)<\/li>\n  <li><strong>Design:<\/strong> 51 terminal cancer patients received either a low dose (1\u20133 mg) or a high dose (22\u201330 mg) of psilocybin in a controlled setting.<\/li>\n  <li><strong>Results:<\/strong> 80% reported significant reductions in anxiety and depression after one session. Effects lasted up to 6 months. Patients experienced greater acceptance and improved quality of life.<\/li>\n\n  <br>\n  <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269881116675513\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7b71e89f elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"7b71e89f\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Kankergerelateerde Distress<\/h3><p class=\"elementor-image-box-description\"> <li><strong>Study:<\/strong> NYU Langone (2016)<\/li>\n  <li><strong>Design:<\/strong> 29 cancer patients received 0.3 mg\/kg psilocybin or a placebo, followed by therapy.<\/li>\n  <li><strong>Results:<\/strong> 60\u201380% of the psilocybin group showed a rapid and sustained reduction in depression and anxiety (up to 7 months). Mystical experiences contributed to these outcomes.<\/li>\n\n  <br>\n  <a href=\"https:\/\/journals.sagepub.com\/doi\/10.1177\/0269881116675512\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-70741c1d elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"70741c1d\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2000\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Alcoholverslaving<\/h3><p class=\"elementor-image-box-description\"><li><strong>Study:<\/strong> NYU (2022)<\/li>\n  <li><strong>Design:<\/strong> 95 participants received two doses of psilocybin (25 mg\/70 kg) along with additional therapy.<\/li>\n  <li><strong>Results:<\/strong> The psilocybin group drank 83% less heavily in the 8 months following treatment, compared to 51% in the control group. This suggests increased motivation and self-awareness.<\/li>\n\n  <br>\n  <a href=\"https:\/\/jamanetwork.com\/journals\/jamapsychiatry\/fullarticle\/2795625\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a>\n<\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6c862df7 elementor-position-left elementor-vertical-align-middle elementor-widget elementor-widget-image-box\" data-id=\"6c862df7\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><img decoding=\"async\" width=\"41\" height=\"45\" src=\"https:\/\/health.mymagnolia.nl\/wp-content\/uploads\/sites\/4\/Book-Icon-Health.svg\" class=\"attachment-full size-full wp-image-2001\" alt=\"Book Icon Health\" \/><\/figure><div class=\"elementor-image-box-content\"><h3 class=\"elementor-image-box-title\">Obsessief-Compulsieve Stoornis (OCS)<\/h3><p class=\"elementor-image-box-description\"><li><strong>Study:<\/strong> University of Arizona (2006)<\/li>\n  <li><strong>Design:<\/strong> 9 patients received various dosages of psilocybin.<\/li>\n  <li><strong>Results:<\/strong> Some participants experienced significant improvements without serious side effects. Although the study was small, the results are promising.<\/li>\n\n  <br>\n  <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17196053\/\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"background-color: #4a4a4a;color: white;padding: 5px 24px;border-radius: 999px;text-decoration: none;font-family: sans-serif;font-weight: 600;font-size: 16px\">\n    Read more\n  <\/a>\n<\/ul><\/p><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2ade73fa e-flex e-con-boxed e-con e-parent\" data-id=\"2ade73fa\" data-element_type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-3465b01c e-con-full e-flex e-con e-child\" data-id=\"3465b01c\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-3d237b6e e-con-full e-flex e-con e-child\" data-id=\"3d237b6e\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-22f880a0 elementor-widget elementor-widget-heading\" data-id=\"22f880a0\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">General Observations<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c671f21 elementor-widget elementor-widget-text-editor\" data-id=\"3c671f21\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The studied applications of psilocybin consistently show that, within a therapeutic framework, the substance can lead to rapid and sometimes long-lasting improvements in depression, anxiety, and addiction-related issues. Safety is considered high, with mostly mild side effects such as headache or nausea.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2f46a8d7 e-con-full e-flex e-con e-child\" data-id=\"2f46a8d7\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-484ce46f elementor-widget elementor-widget-text-editor\" data-id=\"484ce46f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Ongoing research is exploring broader applications such as PTSD, OCD, chronic pain, and Alzheimer\u2019s disease. While preliminary results are encouraging, further research is needed to confirm effectiveness, optimal dosages, and long-term effects.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Research on Psilocybin An Overview of Completed Studies In recent years, research into psilocybin has yielded promising insights into its potential therapeutic applications. In controlled settings, psilocybin has shown positive effects on a range of mental health conditions. While the results are encouraging, experts caution against the use of psilocybin outside of professional and controlled [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":3371,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"class_list":["post-3695","page","type-page","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/pages\/3695","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/comments?post=3695"}],"version-history":[{"count":10,"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/pages\/3695\/revisions"}],"predecessor-version":[{"id":3807,"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/pages\/3695\/revisions\/3807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/media\/3371"}],"wp:attachment":[{"href":"https:\/\/health.mymagnolia.nl\/en\/wp-json\/wp\/v2\/media?parent=3695"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}